THE PROBLEM
if any of the following sounds familiar, you’re in the right place.
ALiCE® FITS YOUR WORKFLOW
Use our expertise to deliver protein directly, or build your fastest production line.
ALiCE® FITS YOUR WORKFLOW
Use our expertise to deliver protein directly, or build your fastest production line.
AI PROTEIN DEVELOPMENT
ALiCE® produces full length, folded, and functional proteins in record time. Characterize your protein without purifying and get data back faster than ever before.
MEMBRANE PROTEINS
Full Length. Actively inserted into a native membrane environment. High Yields. ALiCE® is uniquely matched for membrane proteins.
FULL-LENGTH MEMBRANE PROTEINS
Not fragments. The real target.
Most membrane protein workflows do not produce full-length proteins. They produce fragments or rely on post-expression insertion into artificial systems. These shortcuts often compromise folding, structure, and function — creating problems that appear later in development.
ALiCE® is different.
Proteins are inserted directly into native membranes during expression through an active biological translocation pathway. This allows full-length membrane proteins to fold, orient, and assemble correctly from the start.
Proven expression of full-length membrane proteins.
No truncation. No aggregation-driven artifacts.
Membrane proteins are notoriously difficult to express. Post-translational approaches often result in misfolded, truncated, or unstable proteins due to delayed membrane insertion. ALiCE® changes the timing. By inserting proteins into membranes during translation, ALiCE enables proper folding as the protein is synthesized—supporting the expression of stable, full-length membrane proteins.
FIND WHERE ALiCE® FITS YOUR WORKFLOW
ALiCE® supports teams across discovery and development, from early research to platform-scale operations. Each use case answers one simple question: Can faster, earlier expression data improve your decisions.
Explore how ALiCE® supports:
- Large Pharma
- BioTech
- CROs and CDMOs
- AI Protein Design Vaccines and CGT
- Agriculture and Food
HOW ALiCE® WORKS
ALiCE® is a cell-free protein expression system developed from eukaryotic cells. Without living cells, but with eukaryotic translation machinery, AliCE® can produce proteins without constraints.
Post translational modifications including disulfide bridges, glycosylation, folding, and membrane protein assembly are included. Beyond screening, reactions can be scaled to multi-liter volumes: ALiCE® is the universal protein production system you need in your lab.
HOW ALiCE®WORKS
ALiCE is a plant-based, cell-free protein expression system. Instead of relying on living cells, it uses a controlled biochemical environment that removes viability constraints.
This enables rapid expression, compatibility with difficult proteins, and direct integration into automated workflows.
Because the system is open and engineerable, it supports novel protein formats, non-canonical amino acids, and membrane protein insertion.
WHY TEAMS SWITCH TO ALiCE®
Traditional expression systems were designed for stability, not speed. HEK, CHO, and CRO workflows require cloning, cell culture, and optimization cycles before expression is confirmed.
ALiCE® removes these delays. Expression begins immediately from DNA, and results arrive while decisions are still inexpensive. If speed, flexibility, and early risk reduction matter, ALiCE® provides a clear advantage.
KNOW WHAT YOU GET BEFORE YOU COMMIT
ALiCE® screening provides clear, structured expression data and optional protein output. Pricing is based on screening scale and format, allowing teams to start small and expand as needed. No hidden optimization cycles. No unexpected delays.
Just answers.
ALiCE® IS NOT FOR EVERYONE
If your protein expresses reliably and timelines are not critical, traditional systems may be sufficient. ALiCE® delivers the greatest value when speed, complexity, or uncertainty are limiting progress.
That focus is intentional.
FIVE MINUTES NOW CAN SAVE YOU MONTHS LATER
Screen your protein with ALiCE® and get expression data while decisions are still flexible.