InnoManContiMod Project

LenioBio will contribute with a project titled “Innovative protein medicine biomanufacturing with Continuous-Modular ALiCE”, and InnoManContiMod is a derivative of this title. The project will focus on further development of the cell-free protein expression system, ALiCE®, as an innovative, rapid and on-demand medicine manufacturing technology with strategic value for Europe, fitting into the mission of HERA.

The key goal for the project includes the following:

• Scaling ALiCE® lysate production by optimising process yields, increasing batch size and transitioning to continuous manufacturing
• Expanding ALiCE® capabilities for targeted classes of protein medicines such as vaccines, multispecific antibodies and growth factors by engineering new functionalities and demonstrating modular protein production methods at scale
• Laying the groundwork for GMP-grade lysate production by establishing analytical qualifications, quality systems, and regulatory filing package

LenioBio will be sharing more updates here as the project progresses to its next step, in line with the defined scope of work.